The mouse seems to keep itself locked to the ship/camera controls at random intervals instead of going to the GUI. It worked to buy things from the shop at first, but after entering and exiting several objects, grabbing stuff from asteroids and firing the anti-matter cannons, the mouse decided to keep itself locked to the camera. The mouse still affects the menus and inventory etc, but it is invisible and also controls the camera. It did this three times after quitting and entering. (Not immediately on start, after doing stuff for a while) This was on a Mac.