Very nice design. Excellent exterior, good overall performance, however:
1. I'd switch to Missile/beam on the turrets. They would have a longer range and faster missiles, also more damage, att he cost of a slightly smaller blast radius.
2. I'd switch the dual nukes to beam support as well. More damage, shorter reload time (45 sec at 100%) and fast, long-range missiles to engage targets from a very safe distance. The drawback is a smaller blast radius.